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biphasic calcium phosphate granules

Microporous Biphasic Calcium Phosphate Granules …

Microporous Biphasic Calcium Phosphate Granules (CP®) Retain Immunological Properties of Bone Marrow-Derived Mesenchymal Stromal Cells and Promote Osteoblastic Differentiation

BoneSigma BCP | Sigma Graft

BoneSigma™ BCP is a bone graft substitute with fully interconnected micropores and macropores. It is a biphasic calcium phosphate (BCP) osteoconductive bioceramic material composed of 60% hydroxyapatite (HAp) and 40% beta-tricalcium phosphate (β-TCP). BoneSigma™ BCP is available in granules.

Bone tissue formation in sheep muscles induced by a biphasic calcium phosphate …

Microporous biphasic calcium phosphate granules (CP, TricOs , Baxter BioSciences BioSurgery, Vienna Austria) measuring 1–2 mm in diameter and having a 60/40 hydroxyapatite/b-tricalcium phosphate weight ratio were used. The CP granules were pre

Development of BMP-2 immobilized polydopamine …

1/12/2017· Multichannel biphasic calcium phosphate granules (MCG) were used as starting material procured from Innobone Pvt Ltd., S.Korea. MCGs were thoroughly washed with deionized water (DI) before coating. Polydopamine (PD) solution was prepared by mixing dopamine hydrochloride (4 mg/mL, Sigma) with tris(hydroxymethyl)amino-methane (10 mM, Sigma).

Bone regeneration in critical‐sized bone defect …

Biphasic calcium phosphate (BCP) is frequently used as bone substitute and often needs to be coined with autologous bone to gain an osteoinductive property for guided bone regeneration in implant dentistry.

Bone tissue formation in sheep muscles induced by a biphasic calcium phosphate …

Microporous biphasic calcium phosphate granules (CP, TricOs , Baxter BioSciences BioSurgery, Vienna Austria) measuring 1–2 mm in diameter and having a 60/40 hydroxyapatite/b-tricalcium phosphate weight ratio were used. The CP granules were pre

Biphasic calcium phosphate with submicron surface …

A subclass of calcium phosphate materials with submicron surface topography has been shown to be a highly effective bone graft substitute. In this work, a commercially available biphasic calcium phosphate (BCP) with submicron surface topography (MagnetOs; Kuros Biosciences BV) was evaluated in an Ovine model of instrumented posterolateral fusion.

Bone regeneration of multichannel biphasic calcium …

1/6/2019· The present work is to investigate the efficiency of hyaluronic acid (HyA) supplemented biphasic calcium phosphate (BCP) injectable granule to promote the bone regeneration. The effect of adding HyA to the multichannel BCP granule (MCG-HyA) was studied in terms of morphology, chemical structure, porosity, in-vitro and in-vivo biocompatibility, RT-PCR, western blot and compared with MCG.

Developments in injectable multiphasic biomaterials. The …

Calcium phosphate bioceramic granules associated with hydrosoluble polymers were developed as bone substitutes for various maxillofacial and orthopaedic appliions. These injectable bone substitutes, support and regenerate bone tissue and resorb after

Ridge preservation using an in situ hardening biphasic …

The coating of calcium phosphate granules with PLGA results in a stable, solid alloplastic bone substitute, deterring the loss of exposed granules. In contrast, a flap and/or a barrier merane may be necessary to provide the necessary stability and protection for loose particulate bone grafts without self-hardening characteristics.

Characterisation of Mono- and Biphasic Calcium …

Biphasic, Calcium Phosphate, Granules, Hydroxyapatite (HAP), Solubility, β-Tricalcium Phosphate (β-TCP)

Bone regeneration in critical‐sized bone defect enhanced …

Biphasic calcium phosphate (BCP) is frequently used as bone substitute and often needs to be coined with autologous bone to gain an osteoinductive property for guided bone regeneration in implant dentistry. Given the limitations of using autologous bone, bone morphogenetic protein‐2 (BMP2)‐coprecipitated, layer‐by‐layer asseled biomimetic

(PDF) Bioactivity of Biphasic Calcium Phosphate …

Biphasic calcium phosphate granules were coated with gold using a Desk V Sputter (Denton V acuum), and the surface topographies were examined by secondary electrons using a SEM

CP biphasic calcium phosphate granules and tissucol …

These mouldable, self-hardening materials are based on the association of CP Biphasic Calcium Phosphate Granules and Tissucol Fibrin Sealant. The in vivo evaluation of ingrowth in relation to the composite was made in an experiment on rabbits.

Biphasic Calcium Phosphate Granules Concept for …

Abstract: A new biphasic calcium phosphate ceramic material Hydros™ has been developed. The main attractive feature of BCP ceramic is their ability to form a strong direct bond with the host bone resulting in a strong interface. Currently, granules are more and more used in moldable, injectable bone substitutes.

Bone regeneration in critical‐sized bone defect …

Biphasic calcium phosphate (BCP) is frequently used as bone substitute and often needs to be coined with autologous bone to gain an osteoinductive property for guided bone regeneration in implant dentistry.

Developments in injectable multiphasic biomaterials. …

Calcium phosphate bioceramic granules associated with hydrosoluble polymers were developed as bone substitutes for various maxillofacial and orthopaedic appliions. These injectable bone substitutes, support and regenerate bone tissue and resorb after

Frontiers | Bioactivity of Biphasic Calcium Phosphate …

Bioactivity of Biphasic Calcium Phosphate Granules, the Control of a Needle-Like Apatite Layer Formation for Further Medical Device Developments. Biphasic calcium …

In Vitro and In Vivo Evaluation of Nanostructured Biphasic Calcium Phosphate in Granules …

Abstract: Synthetic biphasic calcium phosphate (BCP) granules and powder are biocompatible bio-materials with a well-known capacity for osteoconduction, presenting very satisfactory clinical and histological results. It remains unanswered if the putty to the

A novel hybrid multichannel biphasic calcium …

The objective of the present study was to develop a novel hybrid multichannel biphasic calcium phosphate granule (MCG)-based composite system for cartilage regeneration. First, hyaluronic acid-gelatin (HG) hydrogel was coated onto MCG matrix (MCG-HG).

Enhanced bone healing by improved fibrin‐clot formation …

This study aimed at improving the fibrin‐clotting rate by coating the surface of biphasic calcium phosphate (BCP Enhanced bone healing by improved fibrin‐clot formation via fibrinogen adsorption on biphasic calcium phosphate granules - Kim - 2015 - Clinical Oral Implants Research - Wiley Online Library

(PDF) HAp granules encapsulated oxidized …

Bone repair in the critical size defect zone using 3D hydrogel scaffold is still a challenge in tissue engineering field. A novel type of hydrogel scaffold coining ceramic and polymer materials, therefore, was fabried to meet this challenge. In

Cytocompatibility of porous biphasic calcium phosphate …

This work aims to evaluate the cytocompatibility of injectable and moldable restorative biomaterials based on granules of dense or porous biphasic calcium phosphates (BCPs) with human primary mesenchymal cells, in order to validate them as tools for stem

(PDF) Bioactivity of Biphasic Calcium Phosphate …

Biphasic calcium phosphate granules were coated with gold using a Desk V Sputter (Denton V acuum), and the surface topographies were examined by secondary electrons using a SEM

Biphasic Calcium Phosphate Granules Concept for …

The granules of biphasic calcium phosphate on the formulation of 70:30 (bTCP/HA) tested in the present work possess physico-chemical properties compatible with an adequate bone substitute, with

Biphasic calcium phosphate with submicron surface …

A subclass of calcium phosphate materials with submicron surface topography has been shown to be a highly effective bone graft substitute. In this work, a commercially available biphasic calcium phosphate (BCP) with submicron surface topography (MagnetOs; Kuros Biosciences BV) was evaluated in an Ovine model of instrumented posterolateral fusion.

Autologous Fibrin Mixed with Biphasic Calcium …

The physical, chemical and biological properties of both biphasic calcium phosphate (BCP) bioceramics and fibrin scaffolds may be cumulated for preparing advanced bone substitutes. Aim of experimental study was to evaluate histological response on implantation of synthetic biphasic HAp/TCP bioceramic granules mixed with autologous plasma derived fibrin scaffold in subcutaneous tissue of …

Biphasic Calcium Phosphate Granules Concept for …

Abstract: A new biphasic calcium phosphate ceramic material Hydros™ has been developed. The main attractive feature of BCP ceramic is their ability to form a strong direct bond with the host bone resulting in a strong interface. Currently, granules are more and more used in moldable, injectable bone substitutes.